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Involvement of ERK1/2 pathway in BPC-157-induced cell proliferation, migration, and tube formation To explore whether the ERK1/2, JNK, or p38 pathway was involved in BPC-157-induced cell proliferation, migration, and tube formation, PD98059 (ERK1/2 inhibitor), SP600125 (JNK inhibitor), and SB203580 (p38 inhibitor) were used

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These factors modulate fibroblast activity, collagen remodeling, and neovascularization

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doi: 10.1016/j.cell.2012.03.042 39 do Carmo SantosM

Final thoughts Combining cagrilintide with tirzepatide represents an experimental approach with theoretical weight loss potential of 20-30% but zero clinical data supporting safety or efficacy