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Common early complaints can include: Nausea or a mildly unsettled stomach Feeling full after smaller meals Reduced interest in food Bloating or belching Indigestion or heartburn Diarrhea Constipation Abdominal discomfort Fatigue These symptoms overlap with adverse reactions listed in current prescribing information for Wegovy and Zepbound

46 , e14203 (2023)

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Thyroid function and obesity

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The dosing regimen selected is based on subject weight and is divided as follows: (a) for subjects 40 kg or less: 500 mg by mouth twice a day for two weeks, then 1000 mg by mouth twice a day for ten weeks