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BMI of 27 or higher (overweight) plus at least one weight-related condition such as type 2 diabetes, high blood pressure (hypertension), high cholesterol (dyslipidemia), obstructive sleep apnea, or cardiovascular disease

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injection-site reactions occur with the weekly subcutaneous formulations

Proactively monitoring your nutrient levels and aiming for a balanced plate can reduce the odds of hair thinning in the months after starting Ozempic

In December 2025, Eli Lilly released Phase 3 clinical trial results showing that retatrutide produced an average weight loss of 28.7% of body weight at 68 weeks