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While its weight loss efficacy may be less pronounced compared to GLP-1, Ozempic, and Wegovy, Trulicity still offers meaningful benefits in terms of weight reduction and glycemic control

Research suggests that GLP-1 receptor activation has neuroprotective effects and can reduce inflammation in the brain, which is linked to depression

Such dose may include about 200 to about 1000 milligrams (mg) per day

Of greater clinical translational significance, RCTs have demonstrated that approximately 26 weeks of liraglutide treatment can significantly reduce hepatic fat content and improve transaminase levels, outperforming lifestyle interventions alone (79)

Two of the three subjects actually gained lean mass while losing substantial body fat

In some embodiments, the otic pharmaceutical formulation comprises between about 50% to about 55% by weight of the triglycerides