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A 2025 Springer review on the topic confirmed that women with PCOS face unique metabolic challenges, including heightened insulin resistance, compounded by obesity that require targeted, not generic, interventions

Fluid-attenuated inversion recovery (FLAIR) imaging can assist in differentiation: Lacunes often exhibit a hyperintense rim due to reactive gliosis or hemosiderin depositionfeatures not typically seen in PVS [37,38,39]

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For more clinical insights, providers can explore resources on Diabetes In Control, which regularly updates treatment strategies

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