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In the OASIS-4 trial, the 25 mg oral dose resulted in an average weight loss of 13.6% after 64 weeks Competition will likely heat up, as Eli Lilly is expected to submit its application to the FDA for the oral dual glucose-dependent insulinopropic polypeptide (GIP)/GLP-1 receptor agonist, orforglipron, by the end of 2025, with potential FDA approval in 2026

77 completed the initial blood draw, and 65 completed Phase 1

These lower drug costs greatly expanded GLP-1 access for the uninsured, underinsured, and those denied drug coverage

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Research suggests that GLP-1 agonism may reduce inflammation, improve mitochondrial biogenesis, stimulate neurogenesis, exert neurotropic effects, and restore neuronal signaling 9 in the central nervous system

After a successful surgery, the team may only need to see the child periodically during their growing years