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With B12 injections, the most common side effects are super mild

Here are the best vitamin B12 injection sites for each method: Subcutaneous B12 injection sites Usually, the best places to give yourself a B12 shot subcutaneously are the abdomen, thigh, and upper arm, as you can see in this illustration: Although not shown above, the buttock is another good site for B12 shots

Raghavan, Ramkripa, et al

Potency degrades after 28-30 days in the refrigerator

Wash your hands and fingernails with soap and warm water for no less than 20 seconds

Patients with severe deficiency may need more frequent injections initially, while those using B12 for wellness optimization may maintain results with monthly treatments