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GHK-Cu has been widely examined in biochemical and dermatological research environments for its influence on collagen production, antioxidant mechanisms, and extracellular matrix regulation

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JCI Insight 5 , e133501 (2020)

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doi: 10.1016/s0002-9343(01)00995-0 52 KupisW.PalygaJ.TomalE.NiewiadomskaE

In cartilage, ECM molecule concentrations increase gradually from the articulating surface towards the bone