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J Crohns Colitis (2016) 10(8):98997.10.1093/ecco-jcc/jjw053 14 PalladinoMABahjatFRTheodorakisEAMoldawerLL

C.KimbleJ

658 Advanced drug delivery systems Innovations in drug delivery aim to enhance the efficacy and specificity of therapeutic agents for DN

doi:10.3389/fnins.2018.00073 175

Treatment should be discontinued immediately if these signs occur and a medical professional should be consulted

Crucially, this glucose-dependent mechanism means insulin is only released when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia compared with some other diabetes medications