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Moreover, while direct comparisons cannot be made without head-to-head trials, some outcomes in diabetes CVOTs have been within the range expected for cardiorenal therapies such as statins, aspirin and antihypertensives [116], despite being added on top of a standard of care that often included these therapies (Fig

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Several medications for postprandial hyperglycemia, such asGI, glinide, DPP4 inhibitors, and GLP-1 analogs, have been commercially available for the past decade and have been shown to exert efficient antihyperglycemic effects and additional protective effects against CVDs [9,10,24]

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