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Investigation of microglia polarization Microglia are the primary immune cells of the CNS, which are crucial in defending against inflammation and injury [50]

Baseline testing should include serum IGF-1, fasting glucose, fasting insulin, HbA1c, comprehensive metabolic panel (to assess liver and kidney function), and lipid panel

Structural characterization of rod Igf-1r / mice rod / To determine whether loss of IGF-1R in rods affects retinal structure, we stained retinal sections from 2-month-old rod Igf-1r / and wild-type littermate mice with hematoxylin and eosin and examined the morphology

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