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Once in the body, IGF-1 LR3 binds to receptors on muscle cells, activating pathways that promote cell proliferation, differentiation, and repair

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Adderall does raise metabolic rate, but only modestly and temporarily

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A pigment change can be measured by colourimetry, melanin assays, histology, gene-expression markers, MC1R pathway activity, or photographic scoring

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Blood Cells Mol Dis 2015;54:164-9

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