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2006 Mar;3(3):153-65.

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It is a 31 amino acid long peptide hormone (7) mainly secreted by enteroendocrine L cells in the distal intestine, alpha cells in the pancreas, and by the preproglucagon (PPG) neurons located in the nucleus of the solitary tract of the caudal brainstem (6)

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doi:10.1016/0014-5793(94)01430-9

Collectively, these results highlight the role of vagal afferents in mediating the metabolic and appetite-regulating effects of peripheral GLP-1, thereby linking gut-derived signals to central regulatory circuits