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The member also noted that serious safety events like liver damage are not detectable through patient self-report, making post-market surveillance inadequate as a substitute for pre-market clinical trials

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While this idea is somewhat simplified, its intriguing His hypothesis suggests that the sudden influx of B12 can kickstart repair processes, and if there has been long-standing damage, the rapid onset of these processes might overwhelm the system, causing a temporary worsening of symptoms