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1 .2.Vildagliptin: Vildagliptin, marketed under the brand name Galvus, is a medication used to manage type 2 diabetes type 2 diabetes mellitus

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Its use can cause side effects like increased appetite, water retention, and fatigue, with rare but serious risks such as joint discomfort

Excess carotenoids can be stored in fatty tissue, liver, and other organs (113, 114)

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By overcoming the low oral bioavailability challenges of peptide GLP-1 RAs, Orforglipron represents a disruptive innovation that could reshape the treatment paradigm for type 2 diabetes