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In a Phase III trial, DefenCath lowered the incidence of catheter-related bloodstream infections by 71% versus heparin alone

Clinical presentations vary depending on the infecting species but commonly include gray patches, black dots, and diffuse alopecia

Injectable delivery bypasses digestion and provides more direct systemic exposure

However, the therapeutic management is extremely challenging, due to the diagnostic and ethical issues presented by many patients and the difficulty in providing a precise prognosis for any individual patient

The cautious approach: Until more research exists, individuals with active cancer, cancer history, or genetic predisposition should avoid BPC-157

TB-500 is likewise not FDA-approved for any indication