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Research from the University of Copenhagen's circadian metabolism lab found that amylin's satiety effect was 22% stronger when administered in the late afternoon (4-6pm) compared to early morning (6-8am), independent of meal timing

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Communication between perioperative teams and prescribing clinicians is particularly important when medication interruption is being considered, as discontinuation may require individualized management plans to maintain glycemic control and therapeutic effectiveness

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PLoS one 6:e22347