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Sports Doping Concerns: Classified as a performance-enhancing peptide and tracked in anti-doping control (PubMed 23084823)

Latvia Research suggests that senescent cells impair proteasome activity in the heart, leading to the accumulation of damaged proteins and reduced cardiac function

Renal and hepatic function are important considerations, as impaired organ function can affect drug metabolism and clearance

Safety Across Different Populations The clinical trial program predominantly enrolled individuals with clinical obesity, providing safety data specifically in this population