Exenatide (Ex-4) and liraglutide are effective in modulating key pathways involved in neurodegeneration, such as apoptosis, mitochondrial function, and autophagy, in models of AD and PD
The propensity score was constructed from age at the index date (continuous), sex, race, region, number of RMS relapses in the preindex period (0, 1, 2+), prior DMT in the preindex period, RMS disability in the preindex period, Deyo-Charlson comorbidity index (DCCI) in the preindex period (continuous), and Psychiatric Diagnosis Group index in the preindex period (continuous)
When I ask patients, about 80% of them report that their symptoms return weeks or months before the next injection is due
The authors found dose-dependent GH release without concurrent rises in prolactin, ACTH, or cortisol at any dose tested
BMC Med 23(1):269
In addition to being able to increase the release of insulin and slow the release of glucogen, GLP-1 has other abilities