[12] Ringseis R, Keller J, Eder K
Given that nearly 2/3 of submissions fail, many patients either must appeal or abandon the claim
The orforglipron trial followed more than 3,000 participants for up to 72 weeks
So they may lose weight initially, but then they plateau, feel worse, or regain the weight when they stop." Another issue is that GLP-1 medications can cause muscle loss and a drop in metabolic rate, which may make long-term weight maintenance more difficult
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