Ideal Candidates Include: People with Metabolic Dysfunction: Type 2 diabetes or pre-diabetes Insulin resistance Metabolic syndrome Obesity or trouble losing weight High triglycerides or cholesterol Fatty liver disease (NAFLD) PCOS (polycystic ovary syndrome) Those Experiencing Low Energy and Fatigue: Chronic fatigue syndrome Mitochondrial dysfunction Low energy despite adequate sleep Poor exercise tolerance or endurance Difficulty recovering from physical activity Athletes and Active Individuals: Wanting to improve endurance capacity Seeking better recovery between training sessions Looking to optimize body composition Aiming to enhance metabolic efficiency Preparing for competitions or events Aging Adults Focused on Longevity: Age 40+ seeking to prevent metabolic decline Interested in health span extension Wanting to maintain muscle mass and function Concerned about age-related disease prevention Seeking cognitive protection as they age Anyone Struggling With: Weight loss resistance despite diet and exercise Visceral (belly) fat accumulation Poor metabolic flexibility Brain fog and cognitive issues Declining physical performance with age Combining MOTS-C With Other Therapies MOTS-C works synergistically with other metabolic optimization strategies, often producing enhanced results when properly stacked
However, every person responds differently to different treatments and surgery may not be necessary if you have a mild case of sagging skin
A French study showed that among 172 elderly patients with vitamin B 12 deficiency, only 2% accounted for inadequate intake,26 while in a hospital-based Chinese study on 52 patients, only 3.8% (median age, 73.5 years) with megaloblastic anaemia (98% had vitamin B 12 deficiency) had inadequate dietary intake.27 However, this can be a problem in strict vegans because animal products are the only dietary source of vitamin B 12
Patient Education Anemia If you have anemia, your blood does not carry enough oxygen to the rest of your body
Reported biochemical potency against human NNMT is in the low-micromolar range with cellular EC values in the low-micromolar range for suppression of 1-MNA and lipogenesis, with selectivity over related methyltransferases and NAD-salvage enzymes [1,6,7]
It may come with weakness, clumsiness (dropping objects), or pain that radiates from the neck or shoulder
