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A small clinical trial found that low-dose semaglutide reduced alcohol cravings and drinking in a controlled setting, suggesting it may help treat alcohol use disorder

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Although, according to the American Diabetes Association, metformin is generally considered the preferred first-line therapy for treating type 2 diabetes, individuals who are intolerant towards metformin can consider GLP-1

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It has been reported that hypnotics such as diazepam and zolpidem enhance GABAergic inhibitory signaling by prolonging the decay time constant of GABA A receptors in various brain region including thalamus, hippocampus, and neocortex [33,34,57-59]