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These trials should investigate blood pressure targets tailored to the nuanced needs of CKD and diabetic patients, taking into account the wider spectrum of comorbidities and the potential for improved outcomes with new treatments

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SGLT2 inhibitors, including empagliflozin, reduce blood glucose and body mass while enhancing hepatic autophagy through the AMPK-TET2 and AMPK/mTOR signaling pathways, thereby attenuating hepatic steatosis

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