The SURPASS-1 trial investigated the efficacy and safety of the three doses of 5, 10, or 15 mg tirzepatide in drug-nave patients with T2D who were not sufficiently controlled with a lifestyle intervention with diet and exercise versus placebo (70)
The inclusion of people with prediabetes represents an effort to prevent diabetes in the Medicare population, "which will ultimately reduce healthcare costs nationally," she added
Women who were not actively protecting against pregnancy because they assumed they were unlikely to conceive need to factor this in
The addition of glucagon receptor agonism has, in early-phase studies, been associated with increased energy expenditure and potential effects on fat stored in the liver
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Other medications you may be taking alongside your GLP-1, including metformin, ACE inhibitors, and beta-blockers, can also cause hair loss and should be reviewed