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This bypasses the gastrointestinal tract, which can be beneficial as it avoids the first-pass metabolism in the liver, potentially increasing the bioavailability of glutathione

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Probiotics can convert polyphenols present in fruits and vegetables, for example, into bioactive compounds with antioxidant properties

Overdose depletes glutathione entirely, but even therapeutic doses can increase glutathione turnover and sometimes lower antioxidant capacity