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Evidence points to the 2-hydroxyestrone metabolite as perhaps the safest estrogen metabolite, so it earns the label of good estrogen, although it is not without potential problems

Semaglutide acts like GLP-1 (a gut hormone) to: Increase insulin production Decrease glucagon synthesis Delay gastric emptying Suppress hunger

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[DOI] [PubMed] [Google Scholar] Cantin AM, Hubbard RC, et al