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[30] This effect may be due to the strong coordination between benzimidazole and the central cobalt atom, pulling it down into the plane of the corrin ring

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It is the first membrane-permeable, selective inhibitor of nicotinamide N-methyltransferase (NNMT), developed at the University of Texas in 2017

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: drugs that may affect blood cell production (e.g., chloramphenicol, anti-cancer drugs, HIV drugs), other vitamins/nutritional supplements (especially folic acid)

Primary Research Applications Metabolic Pathway Research: Utilized in controlled in-vitro models to study metabolic regulation, energy balance, and intracellular signaling mechanisms