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[3] This does not mean the drug "failed." It means obesity is a chronic condition requiring long-term management, a principle stated directly in the Endocrine Society's 2022 pharmacological management guidelines: "Patients should be counseled that pharmacotherapy for obesity is generally required long-term, similar to pharmacotherapy for hypertension or dyslipidemia." [4] Women considering Amble should factor long-term medication costs into their decision, not just the first 6 months

- MOTS-c Mitochondrial peptide (16 aa), Lee 2015 Cell Metab publication

doi: 10.3390/cancers12123642 71 WangDDuBoisRN

Eat smaller meals, stay hydrated, and avoid heavy or greasy foods around dose day

Accessed July 22, 2024

One food monitor did not work for one mouse in vehicle group