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Bioinformatics NCBI BLASTP ( was used to search for GR homolog in the sequenced genome of A

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For example, IB kinase (IKK) promotes the ubiquitination of NRF2 by activating the phosphorylation of CYLD, which in turn inhibits CYLDs deubiquitination activity, further exacerbating oxidative stress damage in the kidneys of obesity-related nephropathy (ORN) [19]

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