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doi:10.1038/s41423-024-01208-z

Research Highlights Exercise-Mimetic Research Preclinical studies suggest SLU-PP-332 can activate aerobic exercise-like gene programs in skeletal muscle models

IM protocols should alternate between the left and right deltoid or vastus lateralis on consecutive administration days

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In contrast, DIO mice in both groups switched from WD to LD each had significantly increased Proteobacteria relative abundance (represented solely by the genus Parasutterella ) compared to both the WD and the LD controls, suggesting that Proteobacteria relative abundance may be largely influenced by stress or the differences in net energy expenditure (or associated body weight changes) caused by the diet switch

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