glutathione and tamoxifen Catabolism of extracellular supplies cysteine to support tumours Oxidative stress contributes to the

J Am Geriatr Soc 1992;40:1197-204

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Certainly, untargeted metabolomics would be useful in ruling out IEMs, but whether or not this kind of testing would be most appropriate incorporated into newborn screening programs versus primarily used for confirmation of a clinical diagnosis remains to be seen (169, 170)

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