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this is touched upon at the end but only in a limited fashion

These studies explored how GLP-1 agonists influence bone metabolism in an osteoporotic state, including effects on bone turnover markers, BMD, and fracture risk

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Murthy CR, Rama Rao KV, Bai G, et al

Additional protein load can also increase kidney workload

Explaining that retatrutide works through triple agonist activation of GIP, GLP-1, and glucagon receptors, producing complementary effects on appetite, gastric emptying, insulin secretion, and energy expenditure doesnt fit in a TikTok caption