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Anaphylaxis has been reported, especially after repeated injection

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Following its physiological action, 1,25(OH)D is further catabolized by CYP24A1 into final metabolites such as calcitroic acid and 1,25(OH)D26,23 lactone, which are subsequently excreted in bile or urine [96, 102].(Fig

Key Takeaways DSIP is a nine-amino-acid neuropeptide with a plasma half-life of roughly 5 to 8 minutes, meaning most of the molecule is degraded before it can reach CNS targets via peripheral injection