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Females reported more pain reduction than males, and the drug was more beneficial for IBS-C and IBS-M (12)

The best option depends on factors such as BMI, medical history, lifestyle preferences, long-term goals, and personal comfort with surgery or medication-based treatment

Last reviewed: May 31, 2026 Last updated: May 31, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

TEE was 13.6% lower in the weight-matched group versus amycretin (means SEM (kcal): weight matched: 1294 57.3, amycretin: 1498 63.6 kcal

However, this lipid side chain also influences the peptide's solubility and susceptibility to temperature-induced aggregation

Overall, adults ages 50 to 64 were most likely to have used GLP-1 drugs, but younger adults were more likely to use them solely for weight loss, according to the KFF survey