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The Molecular Mechanisms of Ferroptosis and Its Role in Cardiovascular Disease

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Protein kinase C-mediated heat shock protein beta-1 (HSPB1) phosphorylation can stabilize the actin cytoskeleton, thereby inhibiting TfR1-mediated iron uptake and reducing lipid ROS production to limit ferroptotic cell death [54]

GPCR, G protein-coupled receptors