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Persistent headaches warrant protocol reassessment

Pansini F, Mollica G, Bergamini CM

The antioxidant properties also protect against UV damage and environmental stressors that can cause pigmentation issues

By delivering oxygen in a unique oxidative form, IV ozone helps improve blood flow, reduce inflammation, and support immune function especially in patients with chronic infections, high TPO levels, or autoimmunity-related fatigue

Some protocols split the daily dose into two administrations (morning and evening) to maintain more consistent plasma levels, though definitive human PK data remain sparse as of 2026

Kishor and Sreenivasulu, via metabolizing the varied ROS and their reaction products (Ruiz and Blumwald, 2002