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Most proinflammatory cytokines such as IL-6, IL-1, TNF-, IL-8, and IFN as well as some anti-inflammatory mediators including -aminoisobutyric acid, A20 enzyme, and EPO have been shown to impair adipogenesis, leading to adipocyte hypertrophy, ectopic fat accumulation, and increased risk of IR and T2DM

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Dahl, Kirsten