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In clinical trials, insulin and GLP-1 fixed ratio combinations also showed the potential to reduce a persons daily insulin dose

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doi: 10.1111/j.1530-0277.1996.tb01722.x

Inhibition of these cytokines also reduces surface expression of cellular adhesion molecules, reducing migration of activated lymphocytes into synovial tissue in PsA, and limiting the bone and cartilage damage by proteases released by these inflammatory cells