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The SURMOUNT-4 trial demonstrated that patients who discontinued tirzepatide after achieving weight loss regained significant weight compared to those who continued treatment, though not all weight loss was reversed during the study period

Achieving or approaching your goal weight can improve surgical outcomes, reduce the risk of complications, and allow your surgeon to create results that are more refined and longer lasting

In preclinical studies, GLP-1 receptor agonists caused thyroid C-cell tumours in rodents, though the relevance to humans is unknown

5-rapid amplification of cDNA ends (RACE)-based genome-wide off-target analysis 5-RACE was performed using the SMARTer RACE 5/3 Kit (Takara Bio) according to the manufacturers instructions

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Let saliva pool under your tongue if necessary