Cytochrome P450 4F2 (CYP4F2) initiates -oxidation of tocochromanols, a process that is followed by -oxidation to carboxyethyl hydroxychromanol (CEHC), which can be conjugated with glucuronide or sulfate and excreted in urine or bile
This work was supported by National Natural Science Foundation of China (81801004), Shanxi Province Key Research and Development Program (201903D321148), Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi (2019L0438, 2020L0209), Graduate Education Innovation Project of Shanxi Province (2019SY278, 2020SY243) and Shanxi Medical University School and Hospital of Stomatology (KY201901, KY201906)
K.LiuP.LiB.LiuZ.et al (2024)
Human thyroid C cells are less sensitive to GLP-1 drugs compared to rodent C cells because they have far fewer GLP-1 receptors
By wrapping the glutathione in these liposomes, we protect it from digestion and allow it to be absorbed directly into the cells
Archived from the original on September 27, 2017