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A more abstract risk is the reality that its so easy to get these meds without receiving actual medical care

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The insufficient in vivo studies on semaglutide and limited in vitro research raise concerns about the imperative for more comprehensive investigations into its effects

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Neural Plast 2021:9923537

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GLP-1 medications like Ozempic, Wegovy, and Mounjaro have quickly become some of the most talked-about tools in weight loss

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Ten patients received semaglutide 1.0 mg, and one patient each received semaglutide 0.5 mg, liraglutide 1.2 mg and liraglutide 2.4 mg (maximum tolerated dose)

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Abbreviations ANCOVA: Analysis of covariance BIA: Bioelectrical impedance CPT-1b: Carnitine palmitoyltransferase 1B CV: Coefficient of variation FCHO: Fermentable carbohydrate FPG: Fasting plasma glucose GLP-1: Glucagon-like peptide 1 HOMA-IR: Homeostasis model assessment of insulin resistance IFG: Impaired fasting glucose IGT: Impaired glucose tolerance IHCL: Intrahepatocellular lipid IMCL: Intramyocellular lipid MRI: Magnetic resonance imaging MRS: Magnetic resonance spectroscopy MTT: Meal tolerance test OGTT: Oral glucose tolerance test SCFA: Short-chain fatty acids SEM: Standard error of the mean tAUC: Total area under the curve T2DM: Type 2 diabetes VAS: Visual analogue scales VAT: Visceral adipose tissue 2hPG: 2 h plasma glucose References Orchard TJ, Temprosa M, Goldberg R, Haffner S, Ratner R, Marcovina S, et al

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