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Results Each propensity-score matched group constituted 3424 patients, 45% women, 21% had a history of cardiovascular disease, and 13.9% were treated with sodium-glucose cotransporter-2 inhibitors at baseline

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As thymic involution with age is associated with increased autoimmune disease incidence, supporting thymic function may have preventive value

Immunohistochemistry (IHC) also revealed that the tumor was positive for multiple additional melanocytic lineage markers, including SOX10, S100 protein, MITF, and HMB-45 (Figure 3D) but negative for CK8/18 and synaptophysin

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However, its anorectic effects and impact on weight loss are comparatively modest relative to those observed with GLP-1R agonism