Further, a point related to BPC 157/NO-system relation as well, as the BPC 157 therapy might be the recovery for the disabled heart functioning (myocardial infarction [53], heart failure [87], pulmonary hypertension [88], arrhythmias [40,41,42,47,48,49,50,51,52,53,54,55,56,60,81,89,90,91], and thrombosis prevention and reversal [40,41,42,43,47,48,49,50,51,52,53,54,55,56])
As such, drug screening targeting CBS, CSE or 3-MST has been conducted
J Biotechnol
The copper content of GHK-Cu formulations has been a theoretical safety consideration, given that excessive copper can be toxic - however, the amounts used in cosmetic and research applications are extremely small, the copper is tightly chelated by the peptide (reducing free copper availability), and topical absorption of copper from these products appears minimal and well below levels that would cause systemic copper accumulation or toxicity
J.MirandaM.RomeroF
Pat or press the product into skin rather than rubbing vigorously