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Reticence to go down the obesity path is also borne out by the length of time it took for Eli Lilly to commit to the issue even though they took out a patent early on for many different types of GLP-1, including for the treatment of obesity

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Intravenous administration of TTFD induces a slight increase in tone and a remarkable increase in the amplitude of rhythmic contractions in the jejunal loop of both non-anesthetized and anesthetized dogs for 20 min (253)