Which one is relevant depends on the pathway a given research question targets
An experiment looked at 13 patients with chronic liver disease before and after four weeks of LC treatment (1800 mg/day) and discovered that after LC treatment, free fatty acid levels and whole-body carbohydrate oxidation increased, but whole-body fatty acid and protein oxidation dropped dramatically (Sakai et al., 2016)
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In addition, Tirzepatide may also have more systemic benefits
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This aligns with the mechanism: glucagon receptor activation promotes heat generation through fat oxidation