For the mammalian W-box, residues V177 and V262 allow the binding of WxxW peptides
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Laboratory evaluation revealed elevated complement component C4a and multi-class mycotoxin positivity, including markedly elevated ochratoxin A
However, free iron in mitochondria and the cytoplasm can generate highly oxidative HO, which damages polyunsaturated fatty acids (PUFAs) in the phospholipid bilayer, leading to mitochondrial outer membrane permeabilization (MOMP), ultimately abrogating DNA stability and inducing cell death
A., & Scheff, S