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Liraglutide consistently promoted the growth of Akkermansia muciniphila, a microbe known to support gut barrier integrity and metabolic health

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Variants in FTO (the fat-mass and obesity-associated gene), GLP1R (the GLP-1 receptor gene that tirzepatide partly targets), MC4R (a melanocortin receptor central to satiety), and TCF7L2 (a transcription factor tied to glucose homeostasis) describe the baseline metabolism a dual agonist is prescribed into