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What to watch: Unusual changes in white blood cell count or differential could signal immune activation that warrants attention

Serious adverse effects such as severe abdominal pain (which may indicate pancreatitis), persistent vomiting leading to dehydration, or signs of thyroid tumors (neck mass, difficulty swallowing, persistent hoarseness) require immediate medical attention

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Atrial fibrillation usually requires treatment with antiarrhythmic medications such as beta-blockers or Ca++ channel antagonists