While it transports intracellular glutamate to the extracellular space, system X C transports extracellular cystine into the cell 37, which is then transformed into cysteine for glutathione (GSH) synthesis
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This level of complexity and inconvenience can also be enough to negatively influence adherence
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This ensures compliance with Rybelsus's strict absorption requirements whilst maintaining the convenience of once-daily dosing for both medications
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