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Participants in both treatment groups received counselling on a reduced-calorie diet and increased physical activity

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GLP-1 therapy can help counter part of that pushback by supporting fullness signals and reducing reward driven eating

Artemisinins mode of action involves a two-step mechanism, activation by heme released from parasite hemoglobin digestion, which catalyses the cleavage of artemisinins endoperoxide bond 3 , then the resulting carbon-centred radical kills the parasite by alkylating a large number of parasite molecules, with particular enrichment for proteins in redox pathways 4